Tumor suppressor NDRG2 tips the balance of oncogenic TGF-β via EMT inhibition in colorectal cancer

Transforming growth factor-beta (TGF-β), a pluripotent cytokine expressed in the colon, has a crucial but paradoxical role in colorectal cancer (CRC). TGF-β is a potent proliferation inhibitor of normal colon epithelial cells and acts as a tumor suppressor. However, TGF-β also promotes invasion and...

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Bibliografske podrobnosti
Main Authors: Shen, L, Qu, X, Ma, Y, Zheng, J, Chu, D, Liu, B, Li, X, Wang, M, Xu, C, Liu, N, Yao, L, Zhang, J
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940918/
https://ncbi.nlm.nih.gov/pubmed/24492480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2013.48
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