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Inhibition of 17α-hydroxylase/C17,20 lyase reduces gating deficits consequent to dopaminergic activation

Cogent evidence points to the involvement of neurosteroids in the regulation of dopamine (DA) neurotransmission and signaling, yet the neurobiological bases of this link remain poorly understood. We previously showed that inhibition of 5α-reductase (5αR), a key neurosteroidogenic enzyme, attenuates...

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Detalhes bibliográficos
Main Authors: Frau, Roberto, Bini, Valentina, Pes, Romina, Pillolla, Giuliano, Saba, Pierluigi, Devoto, Paola, Bortolato, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940882/
https://ncbi.nlm.nih.gov/pubmed/24140269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2013.09.014
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