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Novel monodisperse PEGtide dendrons: design, fabrication and evaluation of mannose receptor-mediated macrophage targeting

Novel PEGtide dendrons of generation 1 through 5 (G1.0-5.0) containing alternating discrete poly(ethylene glycol) (dPEG) and amino acid/peptide moieties were designed and developed. To demonstrate their targeting utility as nanocarriers, PEGtide dendrons functionalized with mannose residues were dev...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gao, Jieming, Chen, Peiming, Singh, Yashveer, Zhang, Xiaoping, Szekely, Zoltan, Stein, Stanley, Sinko, Patrick J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940669/
https://ncbi.nlm.nih.gov/pubmed/23808323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc400011v
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