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Zscan4 Is Regulated by PI3-Kinase and DNA-Damaging Agents and Directly Interacts with the Transcriptional Repressors LSD1 and CtBP2 in Mouse Embryonic Stem Cells

The Zscan4 family of genes, encoding SCAN-domain and zinc finger-containing proteins, has been implicated in the control of early mammalian embryogenesis as well as the regulation of pluripotency and maintenance of genome integrity in mouse embryonic stem cells. However, many features of this enigma...

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Autors principals: Storm, Michael P., Kumpfmueller, Benjamin, Bone, Heather K., Buchholz, Michael, Sanchez Ripoll, Yolanda, Chaudhuri, Julian B., Niwa, Hitoshi, Tosh, David, Welham, Melanie J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940611/
https://ncbi.nlm.nih.gov/pubmed/24594919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089821
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