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Zscan4 Is Activated after Telomere Shortening in Mouse Embryonic Stem Cells

ZSCAN4 is a DNA-binding protein that functions for telomere elongation and genomic stability. In vivo, it is specifically expressed at the two-cell stage during mouse development. In vitro, it is transiently expressed in mouse embryonic stem cells (ESCs), only in 5% of the population at one time. He...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Nakai-Futatsugi, Yoko, Niwa, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834046/
https://ncbi.nlm.nih.gov/pubmed/26997646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.02.010
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