Treadmill exercise reverses dendritic spine loss in direct and indirect striatal medium spiny neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson’s disease

Exercise has been shown to be beneficial for Parkinson’s disease (PD). A major interest in our lab has been to investigate how exercise modulates basal ganglia function and modifies disease progression. Dopamine (DA) depletion leads to loss of dendritic spines within the caudate nucleus and putamen...

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Detalhes bibliográficos
Main Authors: Toy, William A., Petzinger, Giselle M., Leyshon, Brian J., Akopian, Garnik K., Walsh, John P., Hoffman, Matilde V., Vučković, Marta G., Jakowec, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940446/
https://ncbi.nlm.nih.gov/pubmed/24316165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.11.017
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