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Admixture Mapping and Subsequent Fine-Mapping Suggests a Biologically Relevant and Novel Association on Chromosome 11 for Type 2 Diabetes in African Americans

Type 2 diabetes (T2D) is a complex metabolic disease that disproportionately affects African Americans. Genome-wide association studies (GWAS) have identified several loci that contribute to T2D in European Americans, but few studies have been performed in admixed populations. We first performed a G...

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Detalhes bibliográficos
Main Authors: Jeff, Janina M., Armstrong, Loren L., Ritchie, Marylyn D., Denny, Joshua C., Kho, Abel N., Basford, Melissa A., Wolf, Wendy A., Pacheco, Jennifer A., Li, Rongling, Chisholm, Rex L., Roden, Dan M., Hayes, M. Geoffrey, Crawford, Dana C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940426/
https://ncbi.nlm.nih.gov/pubmed/24595071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086931
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