Replication of SCN5A Associations with Electrocardio-graphic Traits in African Americans from Clinical and Epidemiologic Studies

The NAv1.5 sodium channel α subunit is the predominant α-subunit expressed in the heart and is associated with cardiac arrhythmias. We tested five previously identified SCN5A variants (rs7374138, rs7637849, rs7637849, rs7629265, and rs11129796) for an association with PR interval and QRS duration in...

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Published in:Evol Comput Mach Learn Data Min Bioinform
Main Authors: Jeff, Janina M., Brown-Gentry, Kristin, Goodloe, Robert, Ritchie, Marylyn D., Denny, Joshua C., Kho, Abel N., Armstrong, Loren L., McClellan, Bob, Mayo, Ping, Allen, Melissa, Jin, Hailing, Gillani, Niloufar B., Schnetz-Boutaud, Nathalie, Dilks, Holli H., Basford, Melissa A., Pacheco, Jennifer A., Jarvik, Gail P., Chisholm, Rex L., Roden, Dan M., Hayes, M. Geoffrey, Crawford, Dana C.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4290789/
https://ncbi.nlm.nih.gov/pubmed/25590050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-662-45523-4_76
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