Secreted frizzled-related protein-5 (sFRP-5) is epigenetically downregulated and functions as a tumor suppressor in kidney cancer

Secreted frizzled-related protein-5 (sFRP-5) has been identified as one of the secreted antagonists that bind Wnt protein. However, the functional significance of sFRP-5 in renal cell cancer (RCC) has not been reported. We hypothesized that sFRP-5 may be epigenetically downregulated through DNA meth...

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Bibliografiske detaljer
Main Authors: Kawakami, Kazumori, Yamamura, Soichiro, Hirata, Hiroshi, Ueno, Koji, Saini, Sharanjot, Majid, Shahana, Tanaka, Yuichiro, Kawamoto, Ken, Enokida, Hideki, Nakagawa, Masayuki, Dahiya, Rajvir
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940353/
https://ncbi.nlm.nih.gov/pubmed/20340127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25357
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