MicroRNA-34a suppresses malignant transformation by targeting c-Myc transcriptional complexes in human renal cell carcinoma

We investigated the functional effects of microRNA-34a (miR-34a) on c-Myc transcriptional complexes in renal cell carcinoma. miR-34a down-regulated expression of multiple oncogenes including c-Myc by targeting its 3′ untranslated region, which was revealed by luciferase reporter assays. miR-34a was...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yamamura, Soichiro, Saini, Sharanjot, Majid, Shahana, Hirata, Hiroshi, Ueno, Koji, Chang, Inik, Tanaka, Yuichiro, Gupta, Ashish, Dahiya, Rajvir
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2012
Gaiak:
Biology, Genetics and Epigenetics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271269/
https://ncbi.nlm.nih.gov/pubmed/22159222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr286
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