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Mismatch repair gene MSH3 polymorphism is associated with the risk of sporadic prostate cancer
PURPOSE: The mismatch repair (MMR) system is a DNA repair mechanism that corrects mispaired bases during DNA replication errors. Cancer cells deficient in the MMR proteins have a 10(2) –10(3)-fold increase in the mutation rate. Single nucleotide polymorphisms (SNPs) of MMR genes have been shown to c...
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| Hoofdauteurs: | , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2008
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3940351/ https://ncbi.nlm.nih.gov/pubmed/18355840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2008.01.009 |
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