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Effect of Drug Release Kinetics on Nanoparticle Therapeutic Efficacy and Toxicity

The effects of nanoparticle (NP) properties, such as size, shape and surface charge, on their efficacy and toxicity have been studied extensively. However, the effect of controlled drug release on NP efficacy and toxicity has not been thoroughly evaluated in vivo. Our study aims to fill this knowled...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sethi, Manish, Sukumar, Rohit, Karve, Shrirang, Werner, Michael E., Wang, Edina C., Moore, Dominic T., Kowalczyk, Sonya R., Zhang, Liangfang, Wang, Andrew Z.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940272/
https://ncbi.nlm.nih.gov/pubmed/24418914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3nr05961h
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