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Identification of a 31,500 molecular weight islet cell protease as cathepsin B.

A method for the preparation of a radioisotopically labeled active-site directed reagent for proteases (125I-Tyr-Ala-Lys-ArgCH2Cl) is described, and an example of its use as a sensitive method for identifying trypsin-like proteases is provided. This high specific activity reagent was then used in an...

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Détails bibliographiques
Auteurs principaux: Docherty, K, Carroll, R, Steiner, D F
Format: Artigo
Langue:Inglês
Publié: 1983
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC394017/
https://ncbi.nlm.nih.gov/pubmed/6344078
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