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Chronic hypoxia impairs extracellular nucleotide metabolism and barrier function in pulmonary artery vasa vasorum endothelial cells

Vascular remodeling plays a pivotal role in a variety of pathophysiological conditions where hypoxia and inflammation are prominent features. Intravascular ATP, ADP and adenosine are known as important regulators of vascular tone, permeability and homeostasis, however contribution of purinergic sign...

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Hlavní autoři: Yegutkin, Gennady G., Helenius, Mikko, Kaczmarek, Elzbieta, Burns, Nana, Jalkanen, Sirpa, Stenmark, Kurt, Gerasimovskaya, Evgenia V.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940057/
https://ncbi.nlm.nih.gov/pubmed/21922294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-011-9234-0
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