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Chronic hypoxia impairs extracellular nucleotide metabolism and barrier function in pulmonary artery vasa vasorum endothelial cells

Vascular remodeling plays a pivotal role in a variety of pathophysiological conditions where hypoxia and inflammation are prominent features. Intravascular ATP, ADP and adenosine are known as important regulators of vascular tone, permeability and homeostasis, however contribution of purinergic sign...

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Detalhes bibliográficos
Main Authors: Yegutkin, Gennady G., Helenius, Mikko, Kaczmarek, Elzbieta, Burns, Nana, Jalkanen, Sirpa, Stenmark, Kurt, Gerasimovskaya, Evgenia V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940057/
https://ncbi.nlm.nih.gov/pubmed/21922294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-011-9234-0
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