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Obesity Activates a Program of Lysosomal-Dependent Lipid Metabolism in Adipose Tissue Macrophages Independently of Classic Activation

Obesity activates a complex systemic immune response that includes the recruitment of macrophages and other immune cells to key metabolic tissues. Current models postulate that obesity and excess lipids classically activate macrophages, polarizing them toward an M1 (inflammatory) state. Little is kn...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Xu, Xiaoyuan, Grijalva, Ambar, Skowronski, Alicja, van Eijk, Marco, Serlie, Mireille J., Ferrante, Anthony W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939841/
https://ncbi.nlm.nih.gov/pubmed/24315368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.11.001
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