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Functional clonal deletion of cytotoxic T-lymphocyte precursors in chimeric thymus produced in vitro from embryonic Anlagen.
Chimeric thymus, formed by fusing the prelymphoid third pharyngeal pouches of fetal mice with fetal liver, have been allowed to develop entirely in vitro. Syngeneic and allogeneic chimeras were prepared and both types of thymus were shown to contain substantial numbers of functional cytotoxic T lymp...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1983
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393970/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6602338/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.10.3045 |
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