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Functional clonal deletion of cytotoxic T-lymphocyte precursors in chimeric thymus produced in vitro from embryonic Anlagen.

Chimeric thymus, formed by fusing the prelymphoid third pharyngeal pouches of fetal mice with fetal liver, have been allowed to develop entirely in vitro. Syngeneic and allogeneic chimeras were prepared and both types of thymus were shown to contain substantial numbers of functional cytotoxic T lymp...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Good, M F, Pyke, K W, Nossal, G J
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1983
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393970/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6602338/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.10.3045
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