Raf kinase inhibitor RKIP inhibits MDA-9/syntenin-mediated metastasis in melanoma

Melanoma differentiation associated gene-9 (MDA-9), also known as syntenin, functions as a positive regulator of melanoma progression and metastasis. In contrast, the Raf kinase inhibitor RKIP, a negative modulator of RAF-stimulated MEKK activation, is strongly downregulated in metastatic melanoma c...

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Главные авторы: Das, Swadesh K., Bhutia, Sujit K., Sokhi, Upneet K., Azab, Belal, Su, Zhao-zhong, Boukerche, Habib, Anwar, Talha, Moen, Erika L., Chatterjee, Devasis, Pellecchia, Maurizio, Sarkar, Devanand, Fisher, Paul B.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939082/
https://ncbi.nlm.nih.gov/pubmed/23066033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0402
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