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Age-related downregulation of the CaV(3.1) T-type calcium channel as a mediator of amyloid beta production

Alzheimer's is a crippling neurodegenerative disease that largely affects aged individuals. Decades of research have highlighted age-related changes in calcium homeostasis that occur before and throughout the duration of the disease, and the contributions of such dysregulation to Alzheimer'...

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Main Authors: Rice, Rachel A., Berchtold, Nicole C., Cotman, Carl W., Green, Kim N.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939046/
https://ncbi.nlm.nih.gov/pubmed/24268883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2013.10.090
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