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Modulation of CaV1.3b L-type calcium channels by M1 muscarinic receptors varies with CaVβ subunit expression

Abstract Objectives We examined whether two G protein-coupled receptors (GPCRs), muscarinic M1 receptors (M1Rs) and dopaminergic D2 receptors (D2Rs), utilize endogenously released fatty acid to inhibit L-type Ca2+ channels, CaV1.3. HEK-293 cells, stably transfected with M1Rs, were used to transientl...

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Auteurs principaux: Mandy L. Roberts-Crowley, Ann R. Rittenhouse
Format: Artigo
Langue:Inglês
Publié: BMC 2018-09-01
Collection:BMC Research Notes
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Accès en ligne:http://link.springer.com/article/10.1186/s13104-018-3783-x
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