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Loss of MEC-17 Leads to Microtubule Instability and Axonal Degeneration

Axonal degeneration arises as a consequence of neuronal injury and is a common hallmark of a number of neurodegenerative diseases. However, the genetic causes and the cellular mechanisms that trigger this process are still largely unknown. Based on forward genetic screening in C. elegans, we have id...

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Detalhes bibliográficos
Main Authors: Neumann, Brent, Hilliard, Massimo A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939029/
https://ncbi.nlm.nih.gov/pubmed/24373971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.12.004
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