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Base substitution mutations induced by metabolically activated aflatoxin B1.

We have determined the base substitutions generated by metabolically activated aflatoxin B1 in the lacI gene of a uvrB- strain of Escherichia coli. By monitoring over 70 different nonsense mutation sites, we show that activated aflatoxin B1 specifically induced GxC leads to TxA transversions. One po...

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Detalhes bibliográficos
Main Authors: Foster, P L, Eisenstadt, E, Miller, J H
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC393894/
https://ncbi.nlm.nih.gov/pubmed/6405385
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