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TRAF6 is a critical regulator of LMP1 functions in vivo

EBV-encoded latent membrane protein 1 (LMP1) is critical for EBV-driven B-cell transformation and most EBV-associated malignancies and is also implicated in exacerbation of autoimmunity. LMP1 functionally mimics the TNFR superfamily member CD40, but LMP1-induced signals and downstream B-cell functio...

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Detalhes bibliográficos
Main Authors: Arcipowski, Kelly M., Stunz, Laura L., Bishop, Gail A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938860/
https://ncbi.nlm.nih.gov/pubmed/24170780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxt052
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