Beneficial Antimicrobial Effect of the Addition of an Aminoglycoside to a β-Lactam Antibiotic in an E. coli Porcine Intensive Care Severe Sepsis Model

This study aimed to determine whether the addition of an aminoglycoside to a ß-lactam antibiotic increases the antimicrobial effect during the early phase of Gram-negative severe sepsis/septic shock. A porcine model was selected that considered each animal’s individual blood bactericidal capacity. E...

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Hlavní autoři: Skorup, Paul, Maudsdotter, Lisa, Lipcsey, Miklós, Castegren, Markus, Larsson, Anders, Jonsson, Ann-Beth, Sjölin, Jan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938751/
https://ncbi.nlm.nih.gov/pubmed/24587365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090441
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