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Mode of bacterial killing affects the inflammatory response and associated organ dysfunctions in a porcine E. coli intensive care sepsis model

BACKGROUND: Sepsis is often treated with penicillin-binding protein 3 (PBP-3) acting β-lactam antibiotics, such as piperacillin-tazobactam, cefotaxime, and meropenem. They cause considerable bacterial structural changes and have in vitro been associated with an increased inflammatory response. In a...

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Detalhes bibliográficos
Publicado no:Crit Care
Main Authors: Skorup, Paul, Maudsdotter, Lisa, Lipcsey, Miklós, Larsson, Anders, Sjölin, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7666448/
https://ncbi.nlm.nih.gov/pubmed/33189146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-020-03303-9
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