Copy Number Variations Burden on miRNA Genes Reveals Layers of Complexities Involved in the Regulation of Pathways and Phenotypic Expression

MicroRNAs are involved in post-transcriptional down-regulation of gene expression. Variations in miRNA genes can severely affect downstream-regulated genes and their pathways. However, population-specific burden of CNVs on miRNA genes and the complexities created towards the phenotype is not known....

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Main Authors: Veerappa, Avinash M., N, Megha Murthy, Vishweswaraiah, Sangeetha, Lingaiah, Kusuma, Suresh, Raviraj V., Nachappa, Somanna Ajjamada, Prashali, Nelchi, Yadav, Sangeetha Nuggehalli, Srikanta, Manjula Arsikere, Manjegowda, Dinesh S., Seshachalam, Keshava B., Ramachandra, Nallur B.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938728/
https://ncbi.nlm.nih.gov/pubmed/24587348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090391
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