Copy number variations burden on miRNA genes reveals layers of complexities involved in the regulation of pathways and phenotypic expression.

MicroRNAs are involved in post-transcriptional down-regulation of gene expression. Variations in miRNA genes can severely affect downstream-regulated genes and their pathways. However, population-specific burden of CNVs on miRNA genes and the complexities created towards the phenotype is not known....

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Autors principals:	Avinash M Veerappa, Megha N Murthy, Sangeetha Vishweswaraiah, Kusuma Lingaiah, Raviraj V Suresh, Somanna Ajjamada Nachappa, Nelchi Prashali, Sangeetha Nuggehalli Yadav, Manjula Arsikere Srikanta, Dinesh S Manjegowda, Keshava B Seshachalam, Nallur B Ramachandra
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2014-01-01
Col·lecció:	PLoS ONE
Accés en línia:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090391&type=printable
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