Serum Bilirubin Concentration in Healthy Adult North-Europeans Is Strictly Controlled by the UGT1A1 TA-Repeat Variants

The major enzyme responsible for the glucuronidation of bilirubin is the uridine 5′-diphosphoglucose glucuronosyltransferase A1 (UGT1A1) enzyme, and genetic variation in the UGT1A1 gene is reported to influence the bilirubin concentration in the blood. In this study, we have investigated which gene-...

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Detalhes bibliográficos
Main Authors: Kringen, Marianne K., Piehler, Armin P., Grimholt, Runa M., Opdal, Mimi S., Haug, Kari Bente F., Urdal, Petter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938665/
https://ncbi.nlm.nih.gov/pubmed/24587300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090248
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