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Rapid and reliable detection of α-globin copy number variations by quantitative real-time PCR
BACKGROUND: Alpha-thalassemia is the most common human genetic disease worldwide. Copy number variations in the form of deletions of α-globin genes lead to α-thalassemia while duplications of α-globin genes can cause a severe phenotype in β-thalassemia carriers due to accentuation of globin chain im...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3904007/ https://ncbi.nlm.nih.gov/pubmed/24456650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2052-1839-14-4 |
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