Death Receptor (DR4) Haplotypes Are Associated with Increased Susceptibility of Gallbladder Carcinoma in North Indian Population

BACKGROUND AND AIM: Defective apoptosis is a hallmark of cancer development and progression. Death receptors (DR4, FAS) and their ligands (TRAIL, FASL) are thought to mediate the major extrinsic apoptotic pathway in the cell. SNPs in these genes may lead to defective apoptosis. Hence, the present st...

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מידע ביבליוגרפי
Main Authors: Rai, Rajani, Sharma, Kiran L., Sharma, Surbhi, Misra, Sanjeev, Kumar, Ashok, Mittal, Balraj
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2014
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938657/
https://ncbi.nlm.nih.gov/pubmed/24587306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090264
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