Death Receptor (DR4) Haplotypes Are Associated with Increased Susceptibility of Gallbladder Carcinoma in North Indian Population

BACKGROUND AND AIM: Defective apoptosis is a hallmark of cancer development and progression. Death receptors (DR4, FAS) and their ligands (TRAIL, FASL) are thought to mediate the major extrinsic apoptotic pathway in the cell. SNPs in these genes may lead to defective apoptosis. Hence, the present st...

Full description

Saved in:
Bibliographic Details
Main Authors: Rai, Rajani, Sharma, Kiran L., Sharma, Surbhi, Misra, Sanjeev, Kumar, Ashok, Mittal, Balraj
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938657/
https://ncbi.nlm.nih.gov/pubmed/24587306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090264
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items