Antibody-Mediated Inhibition of TNFR1 Attenuates Disease in a Mouse Model of Multiple Sclerosis

Tumour necrosis factor (TNF) is a proinflammatory cytokine that is known to regulate inflammation in a number of autoimmune diseases, including multiple sclerosis (MS). Although targeting of TNF in models of MS has been successful, the pathological role of TNF in MS remains unclear due to clinical t...

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Autors principals: Williams, Sarah K., Maier, Olaf, Fischer, Roman, Fairless, Richard, Hochmeister, Sonja, Stojic, Aleksandar, Pick, Lara, Haar, Doreen, Musiol, Sylvia, Storch, Maria K., Pfizenmaier, Klaus, Diem, Ricarda
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938650/
https://ncbi.nlm.nih.gov/pubmed/24587232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090117
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