Antibody-Mediated Inhibition of TNFR1 Attenuates Disease in a Mouse Model of Multiple Sclerosis

Tumour necrosis factor (TNF) is a proinflammatory cytokine that is known to regulate inflammation in a number of autoimmune diseases, including multiple sclerosis (MS). Although targeting of TNF in models of MS has been successful, the pathological role of TNF in MS remains unclear due to clinical t...

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Detalhes bibliográficos
Principais autores: Williams, Sarah K., Maier, Olaf, Fischer, Roman, Fairless, Richard, Hochmeister, Sonja, Stojic, Aleksandar, Pick, Lara, Haar, Doreen, Musiol, Sylvia, Storch, Maria K., Pfizenmaier, Klaus, Diem, Ricarda
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938650/
https://ncbi.nlm.nih.gov/pubmed/24587232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090117
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