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Knockdown of PRKAR1A, the Gene Responsible for Carney Complex, Interferes With Differentiation in Osteoblastic Cells

PRKAR1A is the gene encoding the type 1A regulatory subunit of protein kinase A, and it is the cause of the inherited human tumor syndrome Carney complex. Data from our laboratory has demonstrated that Prkar1a loss causes tumors in multiple cell lineages, including neural crest cells and osteoblasts...

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Bibliografiske detaljer
Main Authors: Zhang, Mei, Manchanda, Parmeet K., Wu, Dayong, Wang, Qianben, Kirschner, Lawrence S.
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938543/
https://ncbi.nlm.nih.gov/pubmed/24506536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1152
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