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NRF2 mitigates radiation-induced hematopoietic death

Fractionated, high-dose total body irradiation (TBI) is used therapeutically to myeloablate and immune suppress patients undergoing hematopoietic stem cell (HSC) transplantation. Acute exposure to ionizing radiation can have fatal effects on the hematopoietic and immune systems. Currently, therapies...

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Detalhes bibliográficos
Autor principal: Chute, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938265/
https://ncbi.nlm.nih.gov/pubmed/24569364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74143
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