Reversal of in situ T-cell exhaustion during effective human antileukemia responses to donor lymphocyte infusion

Increasing evidence across malignancies suggests that infiltrating T cells at the site of disease are crucial to tumor control. We hypothesized that marrow-infiltrating immune populations play a critical role in response to donor lymphocyte infusion (DLI), an established and potentially curative imm...

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Detalhes bibliográficos
Main Authors: Bachireddy, Pavan, Hainz, Ursula, Rooney, Michael, Pozdnyakova, Olga, Aldridge, Julie, Zhang, Wandi, Liao, Xiaoyun, Hodi, F. Stephen, O’Connell, Karyn, Haining, W. Nicholas, Goldstein, Natalie R., Canning, Christine M., Soiffer, Robert J., Ritz, Jerome, Hacohen, Nir, Alyea, Edwin P., Kim, Haesook T., Wu, Catherine J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938152/
https://ncbi.nlm.nih.gov/pubmed/24357730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-08-523001
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