Combined CD4+ Donor Lymphocyte Infusion and Low-Dose Recombinant IL-2 Expand FOXP3+ Regulatory T Cells following Allogeneic Hematopoietic Stem Cell Transplantation

CD4+CD25+FOXP3+ regulatory T cells (Treg) successfully control graft-versus-host-disease (GVHD) in animal models. In humans, incomplete reconstitution of Treg after allogeneic hematopoietic stem cell transplantation (HSCT) has been associated with chronic GVHD. Recent studies have demonstrated that...

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Bibliographische Detailangaben
Hauptverfasser: Zorn, Emmanuel, Mohseni, Mehrdad, Kim, Haesook, Porcheray, Fabrice, Lynch, Allison, Bellucci, Roberto, Canning, Christine, Alyea, Edwin P., Soiffer, Robert J., Ritz, Jerome
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678797/
https://ncbi.nlm.nih.gov/pubmed/19203731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2008.12.494
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