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Inhibition of Stat3 Activation by Sanguinarine Suppresses Prostate Cancer Cell Growth and Invasion

BACKGROUND: Signal transducer and activator of transcription 3 (Stat3) is an oncogenic transcriptional factor that plays a critical role in carcinogenesis and cancer progression and is a potential therapeutic target. Sanguinarine, a benzophenanthridine alkaloid derived primarily from the bloodroot p...

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Detalhes bibliográficos
Main Authors: Sun, Meng, Liu, Chengfei, Nadiminty, Nagalakshmi, Lou, Wei, Zhu, Yezi, Yang, Joy, Evans, Christopher P., Zhou, Qinghua, Gao, Allen C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938016/
https://ncbi.nlm.nih.gov/pubmed/21538419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21409
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