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Loss of cholesterol 7 alpha-hydroxylase activity in vitro in the presence of bivalent metal ions and by dialysis of rat liver microsomes.
A loss in cholesterol 7 alpha-hydroxylase activity [cholesterol 7 alpha-monooxygenase; cholesterol,NADPH:oxygen oxidoreductase (7 alpha-hydroxylating), EC 1.14.13.17] was seen when rat liver microsomes were incubated in the presence of Ca2+, Mg2+, or Mn2+. The loss in enzyme activity was complete wi...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1983
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393780/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6300898/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.8.2175 |
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