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Loss of cholesterol 7 alpha-hydroxylase activity in vitro in the presence of bivalent metal ions and by dialysis of rat liver microsomes.

A loss in cholesterol 7 alpha-hydroxylase activity [cholesterol 7 alpha-monooxygenase; cholesterol,NADPH:oxygen oxidoreductase (7 alpha-hydroxylating), EC 1.14.13.17] was seen when rat liver microsomes were incubated in the presence of Ca2+, Mg2+, or Mn2+. The loss in enzyme activity was complete wi...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Sanghvi, A, Grassi, E, Diven, W
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1983
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393780/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6300898/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.8.2175
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