Pharmacological and Genetic Targeting of the PI4KA Enzyme Reveals Its Important Role in Maintaining Plasma Membrane Phosphatidylinositol 4-Phosphate and Phosphatidylinositol 4,5-Bisphosphate Levels

Phosphatidylinositol 4-kinase type IIIα (PI4KA) is a host factor essential for hepatitis C virus replication and hence is a target for drug development. PI4KA has also been linked to endoplasmic reticulum exit sites and generation of plasma membrane phosphoinositides. Here, we developed highly speci...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Bojjireddy, Naveen, Botyanszki, Janos, Hammond, Gerald, Creech, Donald, Peterson, Richard, Kemp, Daniel C., Snead, Mark, Brown, Randy, Morrison, Alastair, Wilson, Steve, Harrison, Steve, Moore, Chris, Balla, Tamas
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Biochemistry and Molecular Biology 2014
الموضوعات:
Membrane Biology
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937678/
https://ncbi.nlm.nih.gov/pubmed/24415756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.531426
الوسوم: إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة