Flap Endonuclease Activity of Gene 6 Exonuclease of Bacteriophage T7

Flap endonucleases remove flap structures generated during DNA replication. Gene 6 protein of bacteriophage T7 is a 5′–3′-exonuclease specific for dsDNA. Here we show that gene 6 protein also possesses a structure-specific endonuclease activity similar to known flap endonucleases. The flap endonucle...

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Bibliographic Details
Main Authors: Mitsunobu, Hitoshi, Zhu, Bin, Lee, Seung-Joo, Tabor, Stanley, Richardson, Charles C.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Enzymology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937656/
https://ncbi.nlm.nih.gov/pubmed/24394415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.538611
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