Myostatin Induces DNA Damage in Skeletal Muscle of Streptozotocin-induced Type 1 Diabetic Mice

One of the features of uncontrolled type 1 diabetes is oxidative stress that induces DNA damage and cell death. Skeletal muscle atrophy is also considerable in type 1 diabetes, however, the signaling mechanisms that induce oxidative stress culminating in muscle atrophy are not fully known. Here, we...

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Bibliographic Details
Main Authors: Sriram, Sandhya, Subramanian, Subha, Juvvuna, Prasanna Kumar, McFarlane, Craig, Salerno, Monica Senna, Kambadur, Ravi, Sharma, Mridula
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937650/
https://ncbi.nlm.nih.gov/pubmed/24425880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.483115
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