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Functional Cross-talk between Distant Domains of Chikungunya Virus Non-structural Protein 2 Is Decisive for Its RNA-modulating Activity

Chikungunya virus (CHIKV) non-structural protein 2 (nsP2) is a multifunctional protein that is considered a master regulator of the viral life cycle and a main viral factor responsible for cytopathic effects and subversion of antiviral defense. The C-terminal part of nsP2 possesses protease activity...

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Detaylı Bibliyografya
Asıl Yazarlar: Das, Pratyush Kumar, Merits, Andres, Lulla, Aleksei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937639/
https://ncbi.nlm.nih.gov/pubmed/24407286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.503433
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