Adenosine receptor binding: structure-activity analysis generates extremely potent xanthine antagonists.
Structure-activity analysis of alkylxanthine derivatives at adenosine receptor binding sites has been employed to design more potent adenosine receptor antagonists. Receptor affinities of xanthines were determined by measuring inhibition of the binding of N6-[3H]cyclohexyladenosine to bovine brain m...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1983
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393756/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6300892/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.7.2077 |
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