Adenosine receptor binding: structure-activity analysis generates extremely potent xanthine antagonists.

Structure-activity analysis of alkylxanthine derivatives at adenosine receptor binding sites has been employed to design more potent adenosine receptor antagonists. Receptor affinities of xanthines were determined by measuring inhibition of the binding of N6-[3H]cyclohexyladenosine to bovine brain m...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Bruns, R F, Daly, J W, Snyder, S H
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1983
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393756/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6300892/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.7.2077
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