Matrix Metalloproteinase (MMP)-9 in Cancer-Associated Fibroblasts (CAFs) Is Suppressed by Omega-3 Polyunsaturated Fatty Acids In Vitro and In Vivo

Cancer associated fibroblasts (CAFs) are responsible for tumor growth, angiogenesis, invasion, and metastasis. Matrix metalloproteinase (MMP)-9 secreted from cancer stroma populated by CAFs is a prerequisite for cancer angiogenesis and metastasis. Omega-3 polyunsaturated fatty acids (omega-3 PUFA) h...

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Main Authors: Taguchi, Ayumi, Kawana, Kei, Tomio, Kensuke, Yamashita, Aki, Isobe, Yosuke, Nagasaka, Kazunori, Koga, Kaori, Inoue, Tomoko, Nishida, Haruka, Kojima, Satoko, Adachi, Katsuyuki, Matsumoto, Yoko, Arimoto, Takahide, Wada-Hiraike, Osamu, Oda, Katsutoshi, Kang, Jing X., Arai, Hiroyuki, Arita, Makoto, Osuga, Yutaka, Fujii, Tomoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937340/
https://ncbi.nlm.nih.gov/pubmed/24586907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089605
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