Structure of the Membrane Anchor of Pestivirus Glycoprotein E(rns), a Long Tilted Amphipathic Helix

E(rns) is an essential virion glycoprotein with RNase activity that suppresses host cellular innate immune responses upon being partially secreted from the infected cells. Its unusual C-terminus plays multiple roles, as the amphiphilic helix acts as a membrane anchor, as a signal peptidase cleavage...

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Main Authors: Aberle, Daniel, Muhle-Goll, Claudia, Bürck, Jochen, Wolf, Moritz, Reißer, Sabine, Luy, Burkhard, Wenzel, Wolfgang, Ulrich, Anne S., Meyers, Gregor
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937272/
https://ncbi.nlm.nih.gov/pubmed/24586172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003973
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