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Structure of the Membrane Anchor of Pestivirus Glycoprotein E(rns), a Long Tilted Amphipathic Helix
E(rns) is an essential virion glycoprotein with RNase activity that suppresses host cellular innate immune responses upon being partially secreted from the infected cells. Its unusual C-terminus plays multiple roles, as the amphiphilic helix acts as a membrane anchor, as a signal peptidase cleavage...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3937272/ https://ncbi.nlm.nih.gov/pubmed/24586172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003973 |
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