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Selective Disruption of Aurora C Kinase Reveals Distinct Functions from Aurora B Kinase during Meiosis in Mouse Oocytes

Aurora B kinase (AURKB) is the catalytic subunit of the chromosomal passenger complex (CPC), an essential regulator of chromosome segregation. In mitosis, the CPC is required to regulate kinetochore microtubule (K-MT) attachments, the spindle assembly checkpoint, and cytokinesis. Germ cells express...

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Библиографические подробности
Главные авторы: Balboula, Ahmed Z., Schindler, Karen
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937256/
https://ncbi.nlm.nih.gov/pubmed/24586209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004194
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