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High-Resolution Profiling of Stationary-Phase Survival Reveals Yeast Longevity Factors and Their Genetic Interactions

Lifespan is influenced by a large number of conserved proteins and gene-regulatory pathways. Here, we introduce a strategy for systematically finding such longevity factors in Saccharomyces cerevisiae and scoring the genetic interactions (epistasis) among these factors. Specifically, we developed an...

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Detalhes bibliográficos
Main Authors: Garay, Erika, Campos, Sergio E., González de la Cruz, Jorge, Gaspar, Ana P., Jinich, Adrian, DeLuna, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937222/
https://ncbi.nlm.nih.gov/pubmed/24586198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004168
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