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A single point mutation in the listerial betL σ(A)-dependent promoter leads to improved osmo- and chill-tolerance and a morphological shift at elevated osmolarity

Betaine uptake in Listeria monocytogenes is mediated by three independent transport systems, the simplest of which in genetic terms is the secondary transporter BetL. Using a random mutagenesis approach, based on the E. coli XL1 Red mutator strain, we identified a single point mutation in a putative...

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Autori principali: Hoffmann, Roland F, McLernon, Susan, Feeney, Audrey, Hill, Colin, Sleator, Roy D
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937201/
https://ncbi.nlm.nih.gov/pubmed/23478432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bioe.24094
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